Internalization and toxicity of amine and hydroxyl terminated poly(amidoamine) dendrimers to photosynthetic microorganisms
نویسندگان
چکیده
Poly(amidoamine) (PAMAM) dendrimers are hyper-branched polymers with uniform size, defined molecular weight, large internal cavities and a high number of surface groups that make them particularly suitable for a number of biomedical and technological applications [1]. It has been found that surface functionalization is the main factor modulating the toxicity of dendrimers to mammalian cells lines, but their effects for aquatic microorganisms is still largely unknown [2]. We are presenting results on the effect of generation G2, G3 and G4 amine-terminated (–NH2) and hydroxyl terminated (-OH) PAMAM dendrimers towards the green alga Chlamydomonas reindhartii and the cyanobacterium Anabaena PCC7120.
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